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PEPTIDE MODIFICATION



PEPTIDE MODIFICATION
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We can provide the following peptide modification service. 

Modifications at the N-terminus

+ Acetyl

+ Biotin

+ Fluorescein (FAM, FITC)

+ TAMRA

+ Benzyloxycarbonyl (CBZ) (Z)

+ Pyroglutamic acid (Pyr)

+ Octanoic acid

+ Glycolic acid

+ t-butoxycarbonyl (Boc)

+ Fluorenylmethoxycarbonyl (Fmoc)

+ Rhodamine110

+ Benzoic acid

+ PEGylation

+ Myristic acid

 

Modifications at the C-terminus

+ Alcohol

+ Aldehyde

+ Amide

+ Methyl ester

+ Methyl amide

+ Ethyl amide

+ Biotin (Lys or Cys side chain)

+ Benzaldehyde (Lys side chain)

+ Fluorescein (Lys side chain)

+ TAMRA (Lys side chain)

+ pNA

+ Farnesyl (Cys side chain)

 

Unnatural amino acids

+ Acetyl-lysine

+ Amino hexanonic acid (Ahx)

+ Amino isobutyric acid (Aib)

+ Amino benzoic acid

+ Beta alanine

+ Citrulline (Cit)

+ Cyclohexylalanine (Cha)

+ Cyclohexylglycine (Chg)

+ D amino acids

+ Methyl Lysine

+ Dimethyl Lysine

+ Trimethyl Lysine

+ Methyl Arginine

+ Dimethyl Arginine (Symmetric)

+ Dimethyl Arginine (Asymmetric)

+ Isotopically labeled amino acids (D, 13C, 15N)

+ Phospho Ser, Thr, Tyr

+ Napthylalanine (Nal)

+ Gamma amino butyric acid (GABA)

+ Indanylglycine

+ Hydroxyproline (Hyp)

+ N-methyl amino acids

+ Norleucine (Nle)

+ Norvaline (Nva)

+ Fluoro-Phe

+ Phenylglycine (Phg)

 

Other peptide modifications

+ Conjugation to KLH, BSA Ova

+ Cyclisation (head to tail, side chain, disulfide)

+ Peptides anchored to controlled pore glass (CPG)